Meet our

Lab Members

Our lab members are an intelligent and fun bunch from all over the globe. They are all inquisitive, passionate, and ambitious. Continue reading to get to know them better!

Heads of Lab

Jean-Laurent Casanova, MD, PhD

Jean-Laurent was trained as a pediatrician and immunologist and has in practice become a human geneticist studying the pathogenesis of infectious diseases. He cofounded the Laboratory of Human Genetics of Infectious Diseases with Laurent Abel in 2000, five years after he started his own research group at Necker. When Jean-Laurent was appointed Professor at the Rockefeller University in 2008, he and Laurent maintained their lab in Paris, while running their new lab in NY. Jean-Laurent leads his team testing the hypothesis that life-threatening diseases during primary infection can result from inborn errors of immunity. Outside of the lab, Jean-Laurent enjoys riding his bicycle, exploring the boroughs of New York City. He is also an avid mountaineer and alpinist, having climbed peaks in regions as diverse as the Alps, the Atlas, Kabardino-Balkaria, New Zealand, and Patagonia.

Laurent Abel, MD, PhD

Laurent is the Director of Research at INSERM (DRE). Since 2000, he has been co-directing the Laboratory of Human Genetics of Infectious Diseases (Imagine Institute, Necker campus) with Jean-Laurent Casanova. He is studying the human genetics of infectious diseases, with the goal of identifying the main human susceptibility/resistance genes controlling the response to infection by various microbes (in particular, mycobacteria and oncogenic viruses), and the development of the associated infectious diseases. He is a leading expert in genetic epidemiology of infectious diseases and has developed numerous methods in this field. Laurent is also highly knowledgeable in wine and loves to hike in the Alps.

Theme Leaders

Alexandre Alcaïs, MD, PhD

Alexandre Alcaïs, MD, PhD

Paul Bastard, MD, PhD
Paul was trained in pediatrics and immunology. In addition to working in the lab, Paul works as a fellow un pediatric immunology at the Necker Hospital in Paris. He mainly works on the genetic and immunological predisposition to severe viral diseases and mainly focuses on autoantibodies against type I interferons, their causes and consequences. Paul enjoys riding his bike around Paris, and even collected many samples during COVID-19 by bike.

Paul Bastard, MD, PhD

Vivien Béziat, PhD
Vivien holds a PhD in immunology from Marie Curie University (Paris, France). After a post-doctoral training at the Karolinska Institute in Stockholm (Sweden), he joined the Parisian branch of the HGID lab as an assistant professor. He discovered novel inborn errors of immunity underlying hyper-IgE syndrome (ZNF341, IL6ST) and severe papillomavirus infection (CARMIL2, CD28). His work currently focuses on the human genetics of severe muco-cutaneous oncoviral infections.

Vivien Béziat, PhD

Bertrand Boisson, PhD
Bertrand earned his 2003 PhD from UPMC in Paris, specializing in host-pathogen interaction. Following a malaria postdoc at the Pasteur Institute, he shifted to human genetics of infectious disease. Recruited as an Associate Professor in 2015 by INSERM and later as a Staff Scientist in 2022 by The Rockefeller University, his focus lies in uncovering molecular and cellular mechanisms in idiopathic children, including rare immunodeficiencies like EDA-ID, SPAD, CVID, or HIES with invasive pneumococcal and staphylococcal diseases. Beyond science, he enjoys playing and watching basketball.

Bertrand Boisson, PhD

Stéphanie Boisson-Dupuis, PhD
Stéphanie is a geneticist working in the field of primary immunodeficiencies, focusing on susceptibility to mycobacterial disease. She was appointed as group leader in 2006, to investigate the molecular and genetic basis of tuberculosis. Her group provided the proof-of-principal that TB is a genetic disorder, with monogenic rare and common genetic etiologies of TB. She likes traveling for both work and pleasure!

Stéphanie Boisson-Dupuis, PhD

Jacinta Bustamante, MD, PhD
Jacinta is a pediatrician and immunologist by training. She is an Associate Professor (with tenure) in Cellular Biology in Paris Cité University (MCU-PH). She has made outstanding contributions to the field of infectious diseases affecting the myeloid cells (Mendelian susceptibility to mycobacterial disease or MSMD, chronic granulomatous disease or CGD, Whipple’s disease). In addition to her role as MSMD group leader in the research lab, she is also responsible for the diagnosis of inborn error of innate immunity in patients attending the Center for the Study of Primary Immunodeficiencies (CEDI) at Necker Hospital for Sick Children, Paris -France. Jacinta is passionate about football. As a food lover, she enjoys experimenting with cooking and trying out new recipes for empanadas. She finds it therapeutic and a great way to de-stress.

Jacinta Bustamante, MD, PhD

Aurélie Cobat, MD, PhD
Aurélie is a research scientist at INSERM (Chargé de Recherche, CRCN). She was trained in public health, genetic epidemiology and statistical genetics. She is investigating the human genetics of infectious diseases, with the goal of identifying the main human susceptibility/resistance genes controlling the response to infection by various microbes, in particular mycobacteria and viruses. She is also developing statistical methods to improve and optimize the analysis of NGS data. Outside work, Aurélie enjoys cinema, theater, running and playing basketball with her kids.

Aurélie Cobat, MD, PhD

Emmanuelle Jouanguy, PhD
Emmanuelle holds her PhD in immunology from Pierre and Marie Curie University (Paris, France) working on mycobacterial susceptibility and IFNGR1 deficiency with Jean-Laurent. After a post-doctoral training at Jules Hoffman’s lab in Strasbourg (France), on the antiviral immune response in Drosophila, she joined back the HGID lab to develop the virus team. She discovered novel inborn errors of immunity underlying herpetic encephalitis (UNC93B), NK cell deficiency (MCM4, GINS1), epidermodysplasia verruciformis due to beta-HPVs (RhOH, CIB1) and fulminant hepatitis to hepatitis A virus (IL18BP). Now her work focuses on the antiviral immune response in skin and liver. Outside of the lab, Emmanuelle volunteers for an association to assist others.

Emmanuelle Jouanguy, PhD

Tom Le Voyer, MD, PhD
After a completing residency in clinical immunology, Tom joined the lab of Human Genetic of Infectious Diseases in 2019 as PhD student. He mainly works on the genetic and immunological predisposition to severe infectious diseases, including mycobacterial diseases and SARS-CoV-2 infections.

Tom Le Voyer, MD, PhD

Romain Levy, MD, PhD
Romain is a pediatrician working in Necker Hospital for Sick Children in Paris in a unit dedicated to the care of patients with inborn errors of Immunity (IEIs). He completed his PhD in the HGID lab, both in Paris and NYC. He is currently working part time in the hospital and part time in the lab on the genetic basis of IEIs.

Romain Levy, MD, PhD

Anne Puel, PhD

Anne Puel, PhD

Jérémie Rosain PhD
Jeremie has defend his Ph.D in the HGID lab in 2023. He is currently working part time both in a nationwide clinical laboratory dedicated to immunodeficiency and in the research lab in patients with susceptibility to intramacrophagic pathogens.

Jérémie Rosain, PharmaD, PhD

Guillaume Vogt, PhD
Guillaume Vogt earned his PhD in describing mutations responsible of gain of glycosylation in IFNGR2 associated with mycobacterial susceptibility in Jean-Laurent’s lab in Paris. During his post-doctoral training in Carl Nathan’s lab (Weill Medical College, NY, USA), he developed a method on human macrophages differentiation with antimycobacterial activity. Guillaume then returned to Jean-Laurent’s lab in New-York to start a project on Whipple disease and discovered IRF4 as the first genetic etiology. Presently, his understanding is that the contribution of genetics to any human characteristics is major and generally underestimated when not just dogmatically ignored and developed his idea on different topics. Currently, he works in Jean-Laurent’s lab at Imagine Institute to investigate the genetic etiology of appendicitis.

Guillaume Vogt, PhD

Peng Zhang, PhD
Peng Zhang obtained his PhD in computational biology from National University of Singapore. Peng completed his postdoctoral training at The Rockefeller University, where he established an array of computational methods to facilitate the discovery and interpretation of candidate genes and variants underlying human diseases. Peng is enthusiastic about encoding the biological problems into computational programs and translating the computational outcome into biological and clinical implications. Outside work, Peng enjoys soccer, traveling, and exploring new things.

Peng Zhang, PhD

Shen-Ying Zhang, MD, PhD
Shen-Ying received her MD from Shanghai Fudan University and Jiatong University in China, her PhD from the Paris Cite University in France, and was trained as a Clinical Scholar at the Rockefeller University in the United States. She currently leads the team studying inborn errors of immunity underlying severe viral diseases particularly of the brain and the heart, with the hope to achieve a better understanding of human organ-specific protective immunity fight against viruses. Explore the world, explore science. Exciting journeys so far.

Shen-Ying Zhang, MD, PhD

Qian Zhang, MD
Qian is a pediatrician by training. Since completing her residency in Shanghai, she has been studying children with inborn errors of immunity. During her postdoctoral training at the NIH under the mentorship of Drs. Helen Su and Michael Lenardo, she studied children with severe cutaneous viral infections. In 2018, she joined the lab with a research focus on patients with respiratory viral infections. Qian is an avid climber, and her goal in life is to climb at the level of 5.12a/7b!

Qian Zhang, MD

Trainees

Fahd Al Qureshah, PhD

Kasra Askari, BSc

Musa Bolkent, MD, MPh

Matthieu Chaldebas, MSc

Clément Conil, MSc

Julien Dowding, MSc

Théo Falgarone, PhD

Antoine Fayand, MD

Yi Feng, PhD

Elsa Feredj, MD

Adrian Gervais, PhD

Elina Idiiatullina, MD, PhD

Sonia Jangra, PhD

Corentin Le Floc’h, MSc

Danyel Lee, MD, PhD

Hailun (Helen) Li, MSc

Zhiyong Liu, PhD

Seyed Alireza Mahdaviani, MD

Alexis Maillard, MSc

Astrid Marchal, MSc

Vincent Meynier, PhD

Mana Momenilandi, PhD

Haralambos Aris Mourelatos, BSc

Koji Nakajima, MD

Kosuke Noma, MD, PhD

Uni Park, PhD

Jessica Peel, PhD

Khoren Ponsin, MSc

Sinem Unal, MSc

Ahmad Yatim, MD, PhD

Chenglin Zhang, MSc

Administrative Staff

Maya Chrabieh

Candace Clift

Kerel Francis, MSc

Dana Liu

Lazaro Lorenzo, MSc

Yelena Nemirovskaya

Matthew Peoples

Fabricio Trejos

Mark Woollett

Technical Staff

Lucy Bizien, BSc

Soraya Boucherit, MD

Rémi Chevalier, BSc

Caroline Deswarte, MSc

Iris Fagniez, BSc

Maira Gaballa, MSc

Amyrath Geraldo, MSc

Ji Eun (Grace) Han, MSc

Colin Kim, BSc

Candice Lainé, BSc

Clarisse Lemattre, BSc

Mélanie Migaud, PhD

Marcela Moncada Velez, PhD

Léo Pelletier, MSc

Lucien Pereira Estrela

Jacqueline Rose

Yoann Seeleuthner, PhD

Camille Soudé, MSc

Marianna Teplova, PhD

Joseph Vellutini, BSc

Rebecca Wong, MSc

Former Trainees

Avinash Abhyankar, MD, PhD

Frédégonde About, MD, PhD

Hamoud Al-Mousa, MD

Saleh Al-Muhsen, MD

Frédéric Altare, PhD

Carlos Andres Arango Franco

Andrés A. Arias, PhD

Takaki Asano, MD, PhD

Magali Audry, PhD

Paul Bastard, MD, PhD

Aziz Belkadi, PhD

Serkan Belkaya, PhD

Vivien Béziat, PhD

Benedetta Bigio, PhD

Anat Biran, PhD

Lizbeth Blancas-Galicia, MD

Dusan Bogunovic, PhD

Jonathan Bohlen, PhD

Bertrand Boisson, PhD

Stéphanie Boisson-Dupuis, PhD

Alexandre Bolze, PhD

Marion Bonnet, PhD

Edgar Borges De Oliveira, PhD

Barbara Bosch, MD, PhD

Matthieu Bouaziz, PhD

Vanessa Bryant, PhD

Jacinta Bustamante, MD, PhD

Minji Byun, PhD

Melina Casadio (Herman), PhD

Yi Hao Chan, PhD

Ariane Chapgier, PhD

Jie Chen, MD, PhD

Michael Ciancanelli, PhD

Aurélie Cobat, MD, PhD

Francesca Conti, MD, PhD

Emilie Corvilain, PhD

Julien Cottineau, PhD

Sophie Cypowyj, PhD

Ludovic De Beaucoudrey, PhD

Sarah Jill De Jong, PhD

Erika Della-Mina, PhD

Rainer Döffinger, PhD

Scott Drutman, MD, PhD

Céline Eidenschenk, PhD

Lucia Victoria Erazo Borra, PhD

Claire Fieschi, MD, PhD

Orchidée Filipe-Santos (Dos Santos), PhD

Daxing Gao, PhD

Liwei Gao, MD

Eduardo Garcia Reino, PhD

Jean Gaschignard, MD, PhD

Pegah Ghadiri-Ghandil, PhD

Laure Gineau, PhD

Amandine Grandhomme (Crequer), PhD

Audrey Grant, PhD

Antoine Guerin, PhD

Aurélien Guffroy, MD

Gloria Guillermina Guerrero Manriquez, PhD

Yiqi Guo, PhD

Chaïma Gzara, PhD

Tamar Hermesh, PhD

Nicholas Hernandez

Marjorie Hubeau, PhD

Laura Israel, PhD

Yuval Itan, PhD

Fabienne Jabot-Hanin, PhD

Carolyn Jackson, MD

Valentine Jeanne-Julien, PhD

Emmanuelle Jouanguy, PhD

Yasemin Kendir, MD

Gaspard Kerner, PhD

Nacim Kerrouche, MD

Joëlle Khourieh, PhD

Xiao-Fei Kong, MD, PhD

Cecilia Korol, PhD

Alexandra Y. Kreins, MD, PhD

Cheng-Lung Ku, PhD

Fabien Lafaille, PhD

Fanny Lanternier, MD, PhD

Yoon Seung Lee, PhD

Wei-Te Lei, MD

Romain Lévy, MD, PhD

Juan Li, PhD

Hye Kyung Lim, PhD

Daniel Lin, BSc

Yun Ling, MD, PhD

Luyan Liu, PhD

Saul Lugo-Reyes, MD

Majistor Raj Luxman Maglorius Renkilaraj, MD

Nizar Mahlaoui, MD

Jérémy Manry, PhD

Janet Markle, PhD

Ruben Martinez Barricarte, PhD

Marie Materna, PhD

Daniela Matuozzo, PhD

Marcela Moncada-Velez, PhD

Kunihiko Moriya, MD, PhD

Jeanette Mulwa, MD

Angels Natividad-Sancho, PhD

Anna-Lena Neehus, PhD

Alejandro Nieto-Patlán, PhD

Masato Ogishi, MD

Satoshi Okada, MD, PhD

Carmen Oleaga Quintas, PhD

Swathy Ollikara Vasudevan, PhD

Etienne Patin, PhD

Elodie Pauwels, PhD

Vincent Pedergnana, PhD

Simon Pelham, PhD

Rebeca Pérez De Diego, PhD

Malena Pérez Lorenzo, MSc

Quentin Philippot, MD, PhD

Capucine Picard, MD, PhD

Laura Poyhonen, MD, PhD

Carolina Prando, MD, PhD

Anne Puel, PhD

Jocelyn Quistrebert, PhD

Noe Ramirez Alejo, PhD

Franck Rapaport, PhD

Janine Reichenbach, MD

Natascha Remus, MD, PhD

Ellen Renner, MD, PhD

Darawan Rinchai, PhD

Jérémie Rosain, PharmaD, PhD

Arina Samarina, MD

Vanessa Sancho-Shimizu, PhD

András Spaan, MD, PhD

Andras Sziraki, PhD

Estelle Talouarn, PhD

Giraldina Trevejo-Nunez, MD

Victor Urgarte Bornstein, PhD

Quentin Vincent, MD

Guillaume Vogt, PhD

Horst Von Bernuth, MD, PhD

Yi Wang, PhD

Kun Yang, MD, PhD

Rui Yang, MD, PhD

Peng Zhang, PhD

Shen-Ying Zhang, MD, PhD

Qinhua Zhou, MD